Stimulating anti-anxiety brain circuit can calm nerves, study says

By Staff Writer

A recent study on lab mice reveals that scientists may have found a new treatment for anxiety disorders.

The report, which appears in the online version of the journal Nature, shows that by stimulating a distinct brain circuit that is associated with fearfulness, patients may be able to overcome some of their anxious feelings. Researchers said that most anti-anxiety medications on the market attempt to suppress activity in the brain that generates anxiety, which may lead to addictive behaviors or respiratory suppression.

However, the most recent mouse study suggests that by stimulating the anti-anxiety circuit in the amygdala, which is a structure located deep in the medial temporal lobes, scientists can reduce nervous activity in the brain. Past studies have shown that humans and mice who suffer from anxiety disorders have altered connectivity in similar regions within the amygdala.

When the anti-anxiety circuit was stimulated, mice became more comfortable in situations they would typically perceive as dangerous. Scientists hope that these findings can someday help anxious humans overcome severe anxiety that prevents them from enjoying life.

Adolescents who suffer from anxiety or depression may benefit from wilderness therapy programs, many of which provide help for troubled teens.